The central panel shows Christ crowning the Virgin surrounded by saints; while on the left shutter is the Nativity, on the right, the Crucifixion. Above are the Archangel Gabriel and the Virgin Annunciate.

The reverse of the shutters shows scenes from the Birth and Life of the Virgin. These are, from left to right and top to bottom: the Expulsion of Joachim, the Angel appearing to Joachim, the Meeting at the Golden Gate, the Birth of the Virgin, the Presentation of the Virgin, and the Marriage of the Virgin.

This triptych was painted for private devotions and is one of only two works by the artist known to have been made in Lombardy. It is not known for whom it was commissioned. The inclusion of gilded glass (verre eglomisé) in the spandrels of a panel is unusual.